GEO DataSets

(Submitter supplied) Leukotriene B4 (LTB4) is a potent lipid mediator of inflammation, implicated in numerous diseases including atherosclerosis. We have used primary human monocytes, which express both receptors, to analyze transcriptional responses to LTB4. Comparisons were made between LTB4- and vehicle-treated samples at the same time point. The analysis showed that expression of 72 genes was upregulated at least two-fold at two time points. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3088

Platform:

GPL2895

9 Samples

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Analysis of primary monocytes treated for up 16 hours with leukotriene B4 (LTB4) in vitro. LTB4 is a mediator of inflammation. Monocytes express the cell surface receptors BLT1 and BLT2 that mediate the action of LTB4. Results provide insight into the transcriptional response of monocytes to LTB4.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 5 time sets

Platform:

GPL2895

Series:

GSE9332

9 Samples

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(Submitter supplied) CodeLink Human Whole Genome Bioarray targets most of the known and predictive genes of the human genome as it is described today in the public domain. It is comprised of approximately 55 000 30-mer probes designed to conserved exons across the transcripts of targeted genes. These 55 000 probes represent well annotated, full length, and partial human gene sequences from major public databases. CodeLink Human Whole Genome Bioarray probe sequences were selected from the NCBI UniGene build #165, RefSeq database (January 5, 2004 release) and dbEST database (January 8, 2004 release). more...

Organism:

Homo sapiens

7 DataSets

69 Series

3 Related Platforms

1589 Samples

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