GEO DataSets

(Submitter supplied) We report a genome-wide survey of early responses of the mouse heart transcriptome to acute myocardial infarction (AMI). For three regions of the left ventricle (LV), namely ischemic/infarcted tissue (IF), the surviving LV free wall (FW) and the interventricular septum (IVS), 36,899 transcripts were assayed at six time points from 15 min to 48 h post-AMI in both AMI and sham surgery mice. For each transcript, temporal expression patterns were systematically compared between AMI and sham groups, which identified 515 AMI-responsive genes in IF tissue, 35 in the FW, 7 in the IVS, with three genes induced in all three regions. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2329 GDS2330 GDS2331

Platforms:

GPL83 GPL81 GPL82

198 Samples

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Analysis of left heart ventricles (LV) at various time points up to 48 hours following surgically induced acute myocardial infarction (AMI). Ischemic/infarcted tissue, surviving free wall, and the interventricular septum of LV examined. Results provide insight into the molecular pathogenesis of AMI.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 disease state, 7 time, 4 tissue sets

Platform:

GPL82

Series:

GSE4648

66 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. more...

Organism:

Mus musculus

36 DataSets

76 Series

691 Samples

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