(Submitter supplied) 2,3,7,8-TCDD (TCDD) is a reproductive toxicant and endocrine disruptor in nearly all vertebrates, yet the mechanisms by which TCDD induces these reproductive alterations have not been fully characterized. Fish are among the most sensitive vertebrates to the toxic effects of TCDD, and even subtle physiologic changes induced by TCDD can impair reproduction. Previously, we have shown that chronic, sub-lethal exposure to TCDD decreased reproductive capacity, reduced serum estradiol and vitellogenin concentrations, and altered follicular development.
more...- Organism:
- Danio rerio
- Type:
- Expression profiling by array
- Datasets:
-
GDS2927
GDS2928
- Platform:
- GPL1319
- 8 Samples
Download data: CEL, EXP