GSM111895[Accession] - GEO DataSets

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Items: 4

Select item 2000049591.

Expression data from adult Rattus liver

(Submitter supplied) Activation of the pregnane X receptor (NR1I2) by drugs and other xenobiotics stimulates (or suppresses) expression of numerous genes involved in the metabolic elimination of foreign compounds and some toxic endogenous substrates. We used microarray analysis to identify genes whose expression in rat liver was significantly altered by pregnenolone 16alpha-carbonitrile (PCN) treatment. Keywords: a single ip injection of PCN (100 mg/kg), 8 h treatment

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Datasets:: GDS2093 GDS2094
Platforms:: GPL342 GPL341
19 Samples

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Series

Accession:: GSE4959

ID:: 200004959

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20932.

Pregnane X receptor agonist effect on the liver (RAE230A)

Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL341
Series:: GSE4959
10 Samples

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DataSet

Accession:: GDS2093

ID:: 2093

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000003413.

[RAE230A] Affymetrix Rat Expression 230A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...