GSM1138459[Accession] - GEO DataSets

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Items: 4

Select item 2000467931.

An epigenetic signature of developmental potential in neural stem cells and early neurons

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL9185 GPL6885
14 Samples

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Accession:: GSE46793

ID:: 200046793

Select item 2000467922.

An epigenetic signature of developmental potential in neural stem cells and early neurons [ChIP-seq]

(Submitter supplied) A cardinal property of neural stem cells (NSCs) is their ability to adopt multiple fates upon differentiation. The epigenome is widely seen as a read-out of cellular potential and a manifestation of this can be seen in embryonic stem cells (ESCs), where promoters of many lineage-specific regulators are marked by a bivalent epigenetic signature comprising trimethylation of both lysine 4 and lysine 27 of histone H3 (H3K4me3 and H3K27me3, respectively). more...