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Items: 4

1.

Transcriptome analysis reveals molecular profiles associated with evolving steps of monoclonal gammopathies

(Submitter supplied) To gain further insights into the role of the transcriptome deregulation in the transition from a normal plasma cell (NPC) to a clonal PC and from an indolent clonal PC to a malignant PC, we performed gene expression profiling in 20 patients with MGUS, 33 with high-risk SMM and 41 with MM. The analysis showed that 126 genes were differentially expressed in MGUS, SMM and MM as compared to NPC. Interestingly, 17 and 9 out of the 126 significant differentially expressed genes were small nucleolar RNA molecules (snoRNA) and zinc finger proteins. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4968
Platform:
GPL6244
99 Samples
Download data: CEL, PDF
Series
Accession:
GSE47552
ID:
200047552
2.
Full record GDS4968

Monoclonal gammopathies: bone marrow plasma cells

Analysis of plasma cells from patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (MM), or MM. MM is consistently preceded by MGUS/SMM. Results provide insight into molecular mechanisms underlying the transformation from precursor disease to MM.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 disease state sets
Platform:
GPL6244
Series:
GSE47552
99 Samples
Download data: CEL
3.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Homo sapiens
136 DataSets
1836 Series
26 Related Platforms
37544 Samples
Download data
Platform
Accession:
GPL6244
ID:
100006244
4.

Bone-Marrow_NPC_N1588

Organism:
Homo sapiens
Source name:
Bone Marrow Healthy Donor
Platform:
GPL6244
Series:
GSE47552
Dataset:
GDS4968
Download data: CEL
Sample
Accession:
GSM1152352
ID:
301152352
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