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Items: 4

1.

The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation

(Submitter supplied) Located in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all other liver cell types by physical association and / or by producing cytokines and chemokines. In liver disease and folllowing liver transplantation, elevated levels of endotoxin (bacterial lipopolysaccharide: LPS) stimulate HSCs to produce increased amounts of cytokines and chemokines. Transcriptomic analysis of cultured HSCs stimulated with LPS yields a survey of expression changes which potentially modulate the hepatic inflammatory and immune responses.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS5251 GDS5252
Platform:
GPL1355
11 Samples
Download data: CEL, TXT
Series
Accession:
GSE49980
ID:
200049980
2.
Full record GDS5252

Bacterial lipopolysaccharide endotoxin stimulation effect on hepatic stellate cells: time course (experiment 1)

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1, 3, 6, 12, 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 5 time sets
Platform:
GPL1355
Series:
GSE49980
11 Samples
Download data: CEL
3.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...
Organism:
Rattus norvegicus
107 DataSets
723 Series
13 Related Platforms
22744 Samples
Download data
Platform
Accession:
GPL1355
ID:
100001355
4.

Cultured HSCs-LPS-12h-rep1

Organism:
Rattus norvegicus
Source name:
Cultured HSCs-LPS-12h-rep1
Platform:
GPL1355
Series:
GSE49980
Dataset:
GDS5252
Download data: CEL
Sample
Accession:
GSM1211055
ID:
301211055
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