GEO DataSets

(Submitter supplied) Located in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all other liver cell types by physical association and / or by producing cytokines and chemokines. In liver disease and folllowing liver transplantation, elevated levels of endotoxin (bacterial lipopolysaccharide: LPS) stimulate HSCs to produce increased amounts of cytokines and chemokines. Transcriptomic analysis of cultured HSCs stimulated with LPS yields a survey of expression changes which potentially modulate the hepatic inflammatory and immune responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS5251 GDS5252

Platform:

GPL1355

11 Samples

Download data: CEL, TXT

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1, 3, 6, 12, 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 5 time sets

Platform:

GPL1355

Series:

GSE49980

11 Samples

Download data: CEL

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1 and 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL1355

Series:

GSE49980

8 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

746 Series

13 Related Platforms

23030 Samples

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