GEO DataSets

(Submitter supplied) Background: Resistance to platinum-based chemotherapy remains a major impediment in the treatment of serous epithelial ovarian cancer. The objective of this study was to use gene expression profiling to delineate major deregulated pathways and biomarkers associated with the development of intrinsic chemotherapy resistance upon exposure to standard first-line therapy for ovarian cancer. Methods: The study cohort comprised 28 patients divided into two groups based on their varying sensitivity to first-line chemotherapy using progression free survival (PFS) as a surrogate of response. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4950

Platform:

GPL570

28 Samples

Download data: CEL

Analysis of tumors from high-grade serous ovarian cancer patients resistant or sensitive to platinum-based chemotherapy. Tumor samples collected prior to chemotherapy. Results identify a gene expression profile associated with intrinsic chemotherapy resistance.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 10 disease state, 2 specimen sets

Platform:

GPL570

Series:

GSE51373

28 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5642 Series

61 Related Platforms

171144 Samples

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