GSM1283276[Accession] - GEO DataSets

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Items: 4

Select item 2000531631.

Expression data from human monocyte-derived dendritic cells treated or not with interleukin 17A (IL-17A)

(Submitter supplied) IL-17A is a pro-inflammatory cytokine that promotes host defense against infections and contributes to the pathogenesis of chronic inflammatory diseases. Dendritic cells (DC) are antigen-presenting cells responsible for adaptive immune responses. Here, we report that IL-17A induces intense remodeling of lipid metabolism in human monocyte-derived DC, as revealed by microarrays analysis. In particular NR1H3/LXR-a and its target genes were significantly upregulated in response to IL-17A. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5817
Platform:: GPL570
9 Samples

Download data: CEL

Series

Accession:: GSE53163

ID:: 200053163

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 58172.

Interleukin 17A effect on monocyte-derived dendritic cells

Analysis of in vitro-generated dendritic cells (DCs) cultured with interleukin 17A (IL-17A) in the absence or presence of interferon-γ. IL-17A is involved in chronic inflammatory diseases. Results provide insight into the impact of IL-17A on DCs and the role of these DCs in inflammatory disease.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 protocol, 2 time sets

Platform:: GPL570
Series:: GSE53163
9 Samples

Download data: CEL

DataSet

Accession:: GDS5817

ID:: 5817

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...