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Items: 3

1.

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation

(Submitter supplied) The paracaspase Malt1 is a central regulator of antigen receptor signaling that is frequently mutated in human lymphoma. As a scaffold, it assembles protein complexes for NF-kB activation, and its proteolytic domain cleaves negative NF-kB regulators for signal enforcement. Still, the physiological functions of Malt1-protease are unknown. We demonstrate that targeted Malt1-paracaspase inactivation induces a lethal inflammatory syndrome with lymphocyte-dependent neurodegeneration in vivo. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
36 Samples
Download data: TXT
Series
Accession:
GSE55360
ID:
200055360
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
885 Series
16579 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

E6 het 1h

Organism:
Mus musculus
Source name:
T cells 1h stimulated
Platform:
GPL6885
Series:
GSE55360
Download data
Sample
Accession:
GSM1334693
ID:
301334693
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db=gds|term=GSM1334693[Accession]|query=1|qty=2|blobid=MCID_614761a8150cf119915d44d0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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