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Items: 4

1.

Preclinical antitumor activity of ST7612AA1: a novel second generation oral histone deacetylase (HDAC) inhibitor

(Submitter supplied) assess the efficacy of ST7612AA1 oral pan-histone deacetylase inhibitor (HDACi), with respect to various solid and haematological tumors, and to characterize its mechanism of action
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5615
Platform:
GPL10558
12 Samples
Download data: TXT
Series
Accession:
GSE62460
ID:
200062460
2.
Full record GDS5615

Oral histone deacetylase inhibitor ST7612AA1 effect on diffuse large B-cell lymphoma in vitro models

Analysis of lymphoma cell lines DOHH2 (derived from GCB-DLBCL) and TMD8 (derived from ABC-DLBCL) exposed to ST7612AA1 (300nM) for 8 hrs. ST7612AA1 is an oral thiol-based histone deacetylase inhibitor (HDACi). Results provide insight into the molecular mechanisms underlying ST7612AA1 action in DLBCL.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 cell line sets
Platform:
GPL10558
Series:
GSE62460
12 Samples
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3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2824 Series
4 Related Platforms
100076 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

DOHH2-ST-7612-1

Organism:
Homo sapiens
Source name:
DOHH2 cell lines treated with ST7612AA1
Platform:
GPL10558
Series:
GSE62460
Dataset:
GDS5615
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Sample
Accession:
GSM1527313
ID:
301527313
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