GSM154141[Accession] - GEO DataSets

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Items: 3

Select item 2000066771.

A SAGE approach to discovery of apolipoprotein E4 allele-specific genes involved in increased risk in Alzheimer disease

(Submitter supplied) APOE4 allele is a major risk factor for late-onset Alzheimer disease (AD). The mechanism of action of APOE in AD remains unclear. To study the effects of APOE alleles on gene expression in AD, we have analyzed the gene transcription patterns of human hippocampus from APOE3/3, APOE3/4, APOE4/4 AD patients and normal control using Serial Analysis of Gene Expression (SAGE). Using SAGE, we found gene expression patterns in hippocampus of APOE3/4 and APOE4/4 AD patients differ substantially from those of APOE3/3 AD patients. more...

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platforms:: GPL4 GPL1485
6 Samples

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Accession:: GSE6677

ID:: 200006677

PubMed Full text in PMC Similar studies

Select item 1000014852.

SAGE:17:NlaIII:Homo sapiens

(Submitter supplied) This is a virtual platform for longSAGE 17 libraries generated for Homo sapiens using NlaIII as an anchor enzyme. Platform_anchor: NlaIII