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Items: 4

1.

Gene Expression and Biological Processes Influenced By Deletion of Stat3 in pulmonary Alveolar Type II Cells

(Submitter supplied) Deletion of Stat3 induced genes influencing protein metabolism, transport, chemotaxis and apoptosis and decreased the expression of genes mediating lipid synthesis and metabolism. Srebf1 and 2, key regulators of fatty acid and steroid biosynthesis, were decreased in Stat3D/D mice. Stat3 influenced both pro- and anti-apoptotic pathways, regulating and maintaining the balance between a subset of pro- and anti-apoptotic genes that determine cell death or survival. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3106
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE6846
ID:
200006846
2.
Full record GDS3106

Stat3 deficiency effect on pulmonary alveolar type II epithelial cells

Analysis of type II alveolar cells lacking signal transducer and activator of transcription 3 (Stat3). STAT3 mediates gene expression in response to numerous growth factors and cytokines, playing an important role in many cellular processes. Results provide insight into the role of Stat3 in lung.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE6846
6 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4431 Series
40 Related Platforms
57738 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

Wild-type CS_2_16_WT_3

Organism:
Mus musculus
Source name:
SP-C-rtTA/(tetO)7CMV-Cre double transgenic mice
Platform:
GPL1261
Series:
GSE6846
Dataset:
GDS3106
Download data: CEL
Sample
Accession:
GSM157837
ID:
300157837
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