GSM1831736[Accession] - GEO DataSets

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Items: 4

Select item 2000712981.

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL10558 GPL15456
8 Samples

Download data: BEDGRAPH

Series

Accession:: GSE71298

ID:: 200071298

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000712762.

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer [ChIP-Seq]

(Submitter supplied) HOTAIR is up-regulated in tamoxifen-resistant breast cancer tissues compared to their primary counterparts. Mechanistically, HOTAIR is a direct target of ER-mediated transcriptional repression and is thus restored upon the blockade of ER signaling, either by hormone deprivation or tamoxifen treatment.