GSM189478[Accession] - GEO DataSets

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Items: 4

Select item 2000078101.

Comparative analysis of gene expression WT and Nrf2-/- mice Type II cells

(Submitter supplied) We hypothesize that gene expression in the Type II cells of Nrf2+/+ and Nrf2-/- mice are divergent thus contributing the cell growth. More specifically, type II cells from Nrf2-/- mice have increased reactive oxygen species that cause the impaired cell growth. In order to test these hypotheses at the gene expression level, we utilized microarray analysis to examine transcriptional differences between Nrf2+/+ and Nrf2-/- cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2875
Platform:: GPL1261
9 Samples

Download data: CEL

Series

Accession:: GSE7810

ID:: 200007810

Select item 28752.

Nrf2-deficient type II lung epithelial cell response to antioxidant supplementation

Analysis of Nrf2 deficient lung epithelial cells treated with the antioxidant glutathione (GSH). GSH rescues cells from prooxidant-induced lung injury associated with Nrf2 deficiency. Results provide insight into the molecular mechanisms by which Nrf2 regulates cellular protection and proliferation.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE7810
6 Samples

Download data: CEL

DataSet

Accession:: GDS2875

ID:: 2875

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...