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Items: 5

1.

Effect of Synthetic Dietary Triglycerides: a Novel Research Paradigm for Nutrigenomics

(Submitter supplied) Dietary fatty acids have myriads of effects on human health and disease. Many of these effects are likely achieved by altering expression of genes. Several transcription factors have been shown to be responsive to fatty acids, including SREBP-1c, NF-kB, RXRs, LXRs, FXR, HNF4α, and PPARs. However, the relative importance of these transcription factors in regulation of gene expression by dietary fatty acids remains unclear. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
93 Samples
Download data: CEL
Series
Accession:
GSE8396
ID:
200008396
2.

Comprehensive analysis of PPARa-dependent regulation of hepatic lipid metabolism by expression profiling

(Submitter supplied) PPARalpha is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARalpha in hepatic lipid metabolism, many PPARalpha-dependent pathways and genes have yet to be discovered. In order to obtain an overview of PPARalpha-regulated genes relevant to lipid metabolism, and to probe for novel candidate PPARalpha target genes, livers from several animal studies in which PPARalpha was activated and/or disabled were analyzed by Affymetrix GeneChips. more...
Organism:
Homo sapiens; Mus musculus; Rattus norvegicus
Type:
Expression profiling by array
4 related Platforms
47 Samples
Download data: CEL
Series
Accession:
GSE8316
ID:
200008316
3.

Comprehensive analysis of PPARα-dependent regulation of hepatic lipid metabolism by expression profiling - 3

(Submitter supplied) PPARα is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARα in hepatic lipid metabolism, many PPARα-dependent pathways and genes have yet to be discovered. In order to obtain an overview of PPARα-regulated genes relevant to lipid metabolism, and to probe for novel candidate PPARα target genes, livers from several animal studies in which PPARα was activated and/or disabled were analyzed by Affymetrix GeneChips. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
17 Samples
Download data: CEL
Series
Accession:
GSE8292
ID:
200008292
4.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4430 Series
40 Related Platforms
57729 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
5.

liver_wildtype_control_6h_rep2

Organism:
Mus musculus
Source name:
liver_wildtype_control
Platform:
GPL1261
Series:
GSE8292 GSE8316 GSE8396
Download data: CEL
Sample
Accession:
GSM205767
ID:
300205767
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