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Items: 3

1.

C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity

(Submitter supplied) The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA binding domain is highly conserved among the three family members p53, p63 and p73, the C-terminal domains (CTDs) are diverse and subject to alternative splicing and post-translational modification. Here we demonstrate that the CTDs strongly influence DNA binding and transcriptional activity. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1261 GPL571
11 Samples
Download data: CEL, CHP
Series
Accession:
GSE8660
ID:
200008660
2.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
625 Series
12 Related Platforms
23705 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
3.

H1299 Cell line infected with an truncated p73 adenovirus

Organism:
Homo sapiens
Source name:
H1299
Platform:
GPL571
Series:
GSE8660
Download data: CEL, CHP
Sample
Accession:
GSM214762
ID:
300214762
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