GSM214762[Accession] - GEO DataSets

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Items: 3

Select item 2000086601.

C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity

(Submitter supplied) The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA binding domain is highly conserved among the three family members p53, p63 and p73, the C-terminal domains (CTDs) are diverse and subject to alternative splicing and post-translational modification. Here we demonstrate that the CTDs strongly influence DNA binding and transcriptional activity. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array

Platforms:: GPL1261 GPL571
11 Samples

Download data: CEL, CHP

Series

Accession:: GSE8660

ID:: 200008660

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000005712.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...