GSM218362[Accession] - GEO DataSets

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Items: 3

Select item 2000088061.

Pioglitazone treatment of Lethal Yellow mice

(Submitter supplied) Goal of the experiment: To examine differential gene expression in the ovaries of heterozygous Lethal Yellow (C57BL/6J Ay/a) mice treated with vehicle or pioglitazone. Brief description of the experiment: The objective of this study was to use whole mouse genome DNA microarrays (Codelink) to examine gene expression the ovaries of heterozygous Lethal Yellow (C57BL/6J Ay/a) mice. Women with polycystic ovary syndrome (PCOS) treated with thiazolidinediones (TZD), such as pioglitazone, show reduced androgen levels and improved ovulatory function. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2897
8 Samples

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Accession:: GSE8806

ID:: 200008806

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000028972.

GE Healthcare/Amersham Biosciences CodeLink™ Mouse Whole Genome Bioarray

(Submitter supplied) Mice exhibit high similarity to many human biological pathways, making it a key model system for human physiological and toxicological studies in drug discovery applications. The probe sequences, representing well annotated, full length and partial mouse gene sequences, were designed based on sequences selected from the NCBI UniGene build #139, RefSeq database (April 1, 2004 release) and dbEST database (July 31, 2004 release).Well-annotated mRNA or coding sequences were chosen to ensure usefulness for a large range of applications in basic research, biotechnology, and drug development. more...