GSM2283635[Accession] - GEO DataSets

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Items: 4

Select item 2000860891.

Genome-wide binding of posterior HOXA/D transcription factors reveals subgrouping and association with CTCF

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Gallus gallus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL21476
60 Samples

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Series

Accession:: GSE86089

ID:: 200086089

Select item 2000857572.

Genome-wide binding of posterior HOXA/D transcription factors reveals subgrouping and association with CTCF [RNA-Seq]

(Submitter supplied) The homeotic genes (Hox genes) encode transcription factors (HOX-TFs) that are key regulators of animal development. Single and compound deletion of Hox genes in mice revealed that they act in a partially redundant manner to pattern the vertebrate limb. Biochemical screens probing the sequence specificity of the DNA-binding domains showed that HOX-TFs recognize largely similar DNA sequences, but also emphasized the important role of co-factors in HOX DNA-binding. more...