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Items: 4

1.

Comparative Genomics Identifies Gene Targets for Retinoic Acid in the Embryonic Zebrafish Hearts

(Submitter supplied) Retinoic acid (RA) and 2,3,7,8-tetrachlorodibenzo-p-dioxin activate distinct ligand-dependent transcription factors, and both cause cardiac malformation and heart failure in zebrafish embryos. We hypothesized that they cause this response by hyperactivating a common set of genes critical for heart development. To test this, we used microarrays to measure transcripts changes in hearts isolated from zebrafish embryos 1,2,4 and 12 h after exposure to 1μM RA. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Dataset:
GDS2965
Platform:
GPL1319
48 Samples
Download data: CEL, EXP
Series
Accession:
GSE9020
ID:
200009020
2.
Full record GDS2965

Embryonic heart response to retinoic acid and dioxin: time course

Analysis of hearts from embryos treated for up to 12 hours with retinoic acid (RA) or 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Zebrafish embryos treated with RA or TCDD develop cardiac malformation and heart failure.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 4 agent, 4 time sets
Platform:
GPL1319
Series:
GSE9020
48 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2965
ID:
2965
3.

[Zebrafish] Affymetrix Zebrafish Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html The Affymetrix GeneChip Zebrafish Genome Array can be used to study gene expression of over 14,900 Danio rerio transcripts. Sequence information for this array was selected from the following public data sources: RefSeq (July 2003), GenBank (release 136.0, June 2003), dbEST (July 2003), and UniGene (Build 54, June 2003). more...
Organism:
Danio rerio
18 DataSets
133 Series
1 Related Platform
1558 Samples
Download data
Platform
Accession:
GPL1319
ID:
100001319
4.

embryonic hearts, vehicle control treatment, T 2h, biological replicate2

Organism:
Danio rerio
Source name:
Zebrafish embryonic heart at the age of 74hpf old
Platform:
GPL1319
Series:
GSE9020
Dataset:
GDS2965
Download data: CEL, EXP
Sample
Accession:
GSM228906
ID:
300228906
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