GSM267993[Accession] - GEO DataSets

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Items: 4

Select item 2000106341.

Aquaporin-11 knockout effect on kidney

(Submitter supplied) Aquaporin-11 (AQP11), a new member of the aquaporin family, is localized in the endoplasmic reticulum (ER). Aqp11–/– mice neonatally suffer from polycystic kidneys derived from the proximal tubule. Its onset is proceeded by the vacuolization of ER. However, the mechanism for the formation of vacuoles and the development of cysts remain to be clarified. Here, we show that Aqp11–/– mice and polycystic kidney disease animals share a common pathogenic mechanism of cyst formation. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3395
Platform:: GPL1261
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE10634

ID:: 200010634

Select item 33952.

Aquaporin-11 deficiency effect on the kidney

Analysis of kidneys of 1 week old animals lacking aquaporin-11 (AQP11). AQP11 null mutants develop polycystic kidneys. Results provide insight into the molecular basis of cyst formation in kidneys of AQP11 mutants.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE10634
16 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3395

ID:: 3395

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...