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Items: 4

1.

Myocilin effect on retina. Russell-7U24NS043571-02

(Submitter supplied) Glaucoma is a neurodegenerative disease in which vision is lost as a result of the apoptosis of retinal ganglion cells. When the trabecular meshwork cells, that regulate aqueous humor outflow, are stressed as they are in some forms of glaucoma, they considerably up-regulated secretion of a protein called myocilin into the aqueous. The function of this protein is unclear; but since some aqueous humor flows to the posterior of the eye, the effects of myocilin will also be felt by the retinal cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1640
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE1835
ID:
200001835
2.
Full record GDS1640

Myocilin over-secretion effect on the retina

Analysis of retinas of transgenics that secret high levels of myocilin (MYOC) into the aqueous humor of the eye. Results provide insight into the role of myocilin in the pathogenesis of glaucoma.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE1835
4 Samples
Download data: CEL
DataSet
Accession:
GDS1640
ID:
1640
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4424 Series
40 Related Platforms
57658 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

eye, retina: Myoc 2_e1_le1

Organism:
Mus musculus
Source name:
eye, retina
Platform:
GPL1261
Series:
GSE1835
Dataset:
GDS1640
Download data: CEL
Sample
Accession:
GSM32156
ID:
300032156
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