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Items: 3

1.

MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

(Submitter supplied) Proper mitochondrial function plays a central role in cellular metabolism. Various diseases as well as aging are associated with diminished mitochondrial function. Previously, we identified 19 miRNAs putatively involved in the regulation of mitochondrial metabolism in skeletal muscle, a highly metabolically active tissue. In the present study, these 19 miRNAs were individually silenced in C2C12 myotubes using antisense oligonucleotides, followed by measurement of the expression of 27 genes known to play a major role in regulating mitochondrial metabolism. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11533
6 Samples
Download data: CEL
Series
Accession:
GSE116786
ID:
200116786
2.

[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html MoGene-1_1-st-v1.na31.mm9.transcript.csv #%create_date=Fri Aug 27 17:50:02 2010 PDT #%chip_type=MoGene-1_1-st-v1 #%lib_set_name=MoGene-1_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm8 #%genome-lifted_from-version-ncbi=36 #%netaffx-annotation-date=2010-07-15 #%netaffx-annotation-netaffx-build=31 Protocol: see manufacturer's web site
Organism:
Mus musculus
10 DataSets
173 Series
7 Related Platforms
4209 Samples
Download data
Platform
Accession:
GPL11533
ID:
100011533
3.

Control_rep1

Organism:
Mus musculus
Source name:
C2C12 myotubes_7 days of differentiation_24h post transfection with (negative) control
Platform:
GPL11533
Series:
GSE116786
Download data: CEL
Sample
Accession:
GSM3261911
ID:
303261911
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