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Items: 3

1.

Intracellular activation of complement C3 leads to PD-L1 antibody treatment resistance via modulating tumor-associated macrophages

(Submitter supplied) Mounting evidence has highlighted the importance of complement in the construction of an immunosuppressive tumor microenvironment (TME). Tumor cell-derived C3 has been previously reported, however, whether and how it acts on anti-tumor immunity remains to be elucidated. Here, we describe a unique role of tumor cell-derived C3 in suppressing anti-tumor immunity. Tumor cell-derived C3 was activated intracellularly, which results in generation of C3a. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23479
6 Samples
Download data: TXT
Series
Accession:
GSE120274
ID:
200120274
2.

BGISEQ-500 (Mus musculus)

Platform
Accession:
GPL23479
ID:
100023479
3.

TAM_B

Organism:
Mus musculus
Source name:
CT26-Sg-Con implanted tumor
Platform:
GPL23479
Series:
GSE120274
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Sample
Accession:
GSM3397433
ID:
303397433
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db=gds|term=GSM3397433[Accession]|query=1|qty=2|blobid=MCID_66556d1a6c05354989c7d93e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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