GSM358734[Accession] - GEO DataSets

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Items: 3

Select item 2000143391.

Stress-dependent CHIP/Daxx interaction suppresses the p53 apoptotic program

(Submitter supplied) Our previous studies have implicated CHIP as a co-chaperone/ubiquitin ligase, whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP (carboxyl terminus of Hsp70-interacting protein) and Daxx, death domain-associated protein. This interaction interferes with the stress-dependent association of HIPK2 with Daxx, blocking phosphorylation of serine 46 in p53 and inhibiting the p53-dependent apoptotic program. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
24 Samples

Download data: TXT

Series

Accession:: GSE14339

ID:: 200014339

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000072022.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...