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Items: 3

1.

Characterize CREB target genes in different tissue types

(Submitter supplied) The CREB family of transcription factors stimulates cellular gene expression following phosphorylation at a conserved serine (Ser133 in CREB1) in response to cAMP and other extracellular signals. In order to characterize CREB target genes in various tissues, we give a cAMP agonist, forskolin (FSK), to cell lines or primary cultures and monitor the gene expression. To eliminate CREB-independent effects of FSK on cellular gene expression, we employed a dominant negative form of CREB called A-CREB, which dimerizes selectively with and blocks the DNA binding activity of CREB but not other bZIP family members. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
4 related Platforms
27 Samples
Download data: CEL, EXP
Series
Accession:
GSE2060
ID:
200002060
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
3.

primary mouse hepatocyte, forskolin 4hr

Organism:
Mus musculus
Source name:
primary mouse hepatocyte
Platform:
GPL1261
Series:
GSE2060
Download data: CEL, EXP
Sample
Accession:
GSM37501
ID:
300037501
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