GSM3898751[Accession] - GEO DataSets

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Items: 4

Select item 2001330391.

Epigenetic footprint of hepatoblastoma defines a novel integrative molecular classification with clinical implications [RNA-seq]

(Submitter supplied) Hepatoblastoma (HB) is the predominant pediatric liver cancer with limited therapeutic options for patients with aggressive tumors. Nevertheless, it is a rare disease. Here, we performed a high-throughput molecular study of 32 patients with HB and major findings were validated in additional 80 cases. We unveiled an epigenetic footprint including downregulation of RNA-editing, hyperediting of the tumor suppressor BLCAP,14q32 DLK1-DIO3 locus overexpression, DNA hypomethylation and CpG island hypermethylation. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
66 Samples

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Accession:: GSE133039

ID:: 200133039

Select item 2001322192.

Epigenetic footprint of hepatoblastoma defines a novel integrative molecular classification with clinical implications

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by SNP array; Methylation profiling by genome tiling array; Expression profiling by high throughput sequencing