GSM421936[Accession] - GEO DataSets

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Items: 4

Select item 2000167981.

Genes regulated after knock-down of Pirin in U937 cells

(Submitter supplied) Pirin (PIR) is a putative transcriptional regulator whose expression is silenced in cells bearing the AML1/ETO and PML/RAR leukemogenic fusion proteins and is significantly repressed in a large proportion of acute myeloid leukemias. PIR expression increases during in vitro myeloid differentiation of primary hematopoietic precursor cells, and ablation of PIR in the U937 myelomonocytic cell line or in murine primary hematopoietic precursor cells results in impairment of terminal myeloid differentiation. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5254
Platform:: GPL570
4 Samples

Download data: CEL

Series

Accession:: GSE16798

ID:: 200016798

Select item 52542.

Pirin depletion effect on myelomonocytic cell line

Analysis of U937 myelomonocytic cells depleted for Pirin. Pirin is silenced in cells with the acute myeloid leukemia-1 eight-twenty-one and promyelocytic leukemia/retinoic acid receptor leukemogenic fusion proteins. Results provide insight into the role of Pirin in myeloid differentiation.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL570
Series:: GSE16798
4 Samples

Download data: CEL

DataSet

Accession:: GDS5254

ID:: 5254

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...