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Items: 3

1.

Triacylglycerol synthesis enhances macrophage inflammatory function

(Submitter supplied) Macrophages stimulated with lipopolysaccharide (LPS) plus interferon-g (IFNg) accumulate TGs in LDs, and long-chain acylcarnitines. Inhibition of TG synthesis results in diminished LD development, and increased long chain acylcarnitine levels, suggesting that FA fate is balanced between TG and acylcarnitine synthesis. Nevertheless, TG-synthesis is required for inflammatory macrophage function, since its inhibition negatively affects production of proinflammatory IL-1b, IL-6 and PGE2, and phagocytic capacity, and protects against LPS-induced sock in vivo.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21493
12 Samples
Download data: TXT
Series
Accession:
GSE145523
ID:
200145523
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

Stimulated_M1_18h_1

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320176
ID:
304320176
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db=gds|term=GSM4320176[Accession]|query=1|qty=2|blobid=MCID_6281e18a7907e46bfe3c5c41|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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