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Items: 4

1.

Regulatory T cell-mediated resolution of lung injury: Identification of potential target genes via expression profiling

(Submitter supplied) We examined early and late gene expression changes using the IT LPS model of Acute Lung Injury (ALI). In this model, injury peaks at day 4 and is almost completely resolved by day 10 in wild type (WT) C57BL/6 mice. In contrast to the pattern in WT mice, lymphocyte-deficient Rag-1 -/- mice exhibit strikingly delayed resolution despite similar initial injury.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3749
Platform:
GPL4865
24 Samples
Download data: TXT
Series
Accession:
GSE17355
ID:
200017355
2.
Full record GDS3749

Intratracheal lipopolysaccharide (IT LPS)-induced lung injury effect on Rag-1 null, lymphocyte-deficient mutants

Temporal analysis of lungs from recombinase-activating gene-1-deficient (Rag-1 -/-), lymphocyte-deficient animals following acute lung injury. Resolution of acute lung injury is impaired in Rag-1 null mutants. Results provide insight into molecular mechanisms underlying resolution of lung injury.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation, 4 time sets
Platform:
GPL4865
Series:
GSE17355
24 Samples
Download data
3.

Sentrix MouseRef-8 Expression BeadChip (Target ID)

(Submitter supplied) The Sentrix MouseRef-8 BeadChip can be used to study expression of approximately 24,000 well-annotated transcripts from the NCBI RefSeq database. Researchers can generate whole-genome expression profiles for 8 samples in parallel on a single BeadChip. The array is composed of 3 micron features with average feature redundancy of 30-fold. All features are quality controlled by sequential hybridizations process called array decoding. more...
Organism:
Mus musculus
3 DataSets
13 Series
128 Samples
Download data
Platform
Accession:
GPL4865
ID:
100004865
4.

Control (WT) A

Organism:
Mus musculus
Source name:
mouse lung
Platform:
GPL4865
Series:
GSE17355
Dataset:
GDS3749
Download data
Sample
Accession:
GSM433817
ID:
300433817
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