GSM4670498[Accession] - GEO DataSets

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Items: 4

Select item 2001544081.

Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Xenopus laevis

Type:: Expression profiling by RT-PCR; Expression profiling by high throughput sequencing

Platforms:: GPL28865 GPL22393
168 Samples

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Accession:: GSE154408

ID:: 200154408

PubMed Full text in PMC Similar studies

Select item 2001543992.

Robustness of retinoic acid regulatory homeostasis during early development (RNA-seq)

(Submitter supplied) Retinoic acid (RA) is a central developmental signal whose perturbation results in teratogenic outcomes. RA are tightly regulated during early embryonic development to achieve fine-tuning of the instructive and permissive signals regulating multiple developmental processes including head formation. We aim to identify the key mechanisms underlying the homeostatic regulation and tuning of the retinoic acid signaling levels, the disruption of which in the head lead to wide ranging developmental malformations including microcephaly and other craniofacial defects. more...