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Items: 3

1.

SRT1720 extends healthspan and lifespan in diet-induced obese mice

(Submitter supplied) Activation of Sirt1, the mammalian homolog of an NAD+-dependent deacetylase known to modulate lifespan in lower organisms, is thought to hold promise as a strategy for delaying aging in mammals. SRT1720, a novel compound developed as a specific and potent activator of Sirt1, has shown promising effects to glucose homeostasis in short-term studies of rats and mice. Here we show SRT1720 extends both mean and maximum lifespan of mice fed a high-fat diet and has concrete benefits to health including reduced liver steatosis and increased insulin sensitivity and locomotor activity. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
12 Samples
Download data: TXT
Series
Accession:
GSE19102
ID:
200019102
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
881 Series
16514 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

HFD-L-1

Organism:
Mus musculus
Source name:
Mus musculus liver tissue
Platform:
GPL6885
Series:
GSE19102
Download data
Sample
Accession:
GSM473336
ID:
300473336
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db=gds|term=GSM473336[Accession]|query=1|qty=2|blobid=MCID_61008c8a4ea4a464ea5647a4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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