Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

Low dose Leptin (25 ng/hr and 12.5 ng/hr) in ob/ob mice

(Submitter supplied) Ob/ob mice were given 0, 12.5 or 25 ng/hr leptin through an osmotic pump. After 12 days, livers RNA was prepared and illumina microarrays were done. We tested whether leptin can ameliorate diabetes independent of weight loss by defining the lowest dose at which leptin treatment of ob/ob mice reduces plasma [glucose] and [insulin]. We found that a leptin dose of 12.5 ng/hour significantly lowers blood glucose and that 25 ng/hour of leptin normalizes plasma glucose and insulin without significantly reducing body weight, thus establishing that leptin exerts its most potent effects on glucose metabolism. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3653
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE19185
ID:
200019185
2.
Full record GDS3653

ob/ob liver response to low doses of leptin

Analysis of liver from ob/ob animals treated with 12.5 or 25 ng/hour of leptin. Treatment of ob/ob animals with 12.5 ng/hour of leptin lowers blood glucose and that with 25 ng/hour normalizes plasma glucose and insulin without reducing body weight.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 3 dose sets
Platform:
GPL6885
Series:
GSE19185
8 Samples
Download data
DataSet
Accession:
GDS3653
ID:
3653
3.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
881 Series
16514 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
4.

25 ng/hr leptin_8

Organism:
Mus musculus
Source name:
adult male liver, treated with 25 ng/hr leptin
Platform:
GPL6885
Series:
GSE19185
Dataset:
GDS3653
Download data
Sample
Accession:
GSM475616
ID:
300475616
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM475616[Accession]|query=1|qty=2|blobid=MCID_6100d302249b2f375d71a21a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center