GSM48390[Accession] - GEO DataSets

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Items: 4

Select item 2000025571.

Transcriptome Profiling of High Glucose and Glucosamine-Induced Mouse Mesangial Cells

(Submitter supplied) The renal mesangial cells play an important role in the development of diabetic glomerulosclerosis and renal failure. We have previously demonstrated some of the effects of high glucose are mediated via the hexosamine biosynthesis pathway (HBP) in which fructose-6-phosphate is converted to glucosamine-6-phosphate by the rate-limiting enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT). Using Affymetrix murine expression U430 2.0 chips, we examined the global effects of high glucose (HG) and glucosamine (GlcN) on the transcriptomes of a mouse mesangial cell line (MES-13). more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1891
Platform:: GPL1261
6 Samples

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Series

Accession:: GSE2557

ID:: 200002557

Select item 18912.

Glucosamine and high glucose effect on renal mesangial cells

Analysis of renal mesangial MES-13 cells treated with high glucose or glucosamine. Mesangial cells play an important role in the development of diabetic glomerulosclerosis and renal failure. Glucosamine and high glucose mimic the hyperglycemic and hemodynamic insults of diabetic kidney disease.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL1261
Series:: GSE2557
6 Samples

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DataSet

Accession:: GDS1891

ID:: 1891

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...