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Items: 3

1.

Prkar1a haploinsufficiency leads to an overall increase in tumors caused by other genetic defects or chemical induction

(Submitter supplied) [original title] Prkar1a haploinsufficiency in mice leads to an overall increase in tumors caused by other genetic defects or chemical induction We investigated the Prkar1a+/- mice when bred within the Rb1+/- or Trp53+/- genetic backgrounds, or treated with a 2-step skin carcinogenesis protocol. Prkar1a+/-Trp53+/- mice developed more bone sarcomas than Trp53+/- mice (p<0.05) and Prkar1a+/-Rb1+/- mice grew more and larger pituitary and thyroid tumors than Rb1+/- mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
23 Samples
Download data: TXT
Series
Accession:
GSE19576
ID:
200019576
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
885 Series
16579 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

Thyroid Prkar1a+/- Rb1+/--2

Organism:
Mus musculus
Source name:
Thyroid tumor
Platform:
GPL6885
Series:
GSE19576
Download data
Sample
Accession:
GSM490194
ID:
300490194
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