GSM5576034[Accession] - GEO DataSets

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Items: 4

Select item 2001841951.

Placental exosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL30209
12 Samples

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Accession:: GSE184195

ID:: 200184195

PubMed Full text in PMC Similar studies

Select item 2001840202.

Human placental exosomes induce maternal systemic immune tolerance in a monocyte-dependent manner

(Submitter supplied) Maternal immune tolerance toward to the semi-allograft fetus is a prerequisite condition for successful pregnancy. However, the role of maternal monocytes in the induction of systemic immune tolerance is poorly understood. Here we report that placenta facilitates maternal immune tolerance by extruding exosomes. Maternal monocytes were transformed into an immunosuppressive phenotype after taking up exosomes. more...