GSM610772[Accession] - GEO DataSets

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Items: 4

Select item 2000248261.

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL9250 GPL6885
76 Samples

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Series

Accession:: GSE24826

ID:: 200024826

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000221022.

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response (sequencing)

(Submitter supplied) Effective anti-viral immunity depends on the ability of infected cells or cells triggered with virus-derived nucleic acids to produce type I interferon (IFN), which activates transcription of numerous antiviral genes. However, disproportionately strong or chronic IFN expression is a common cause of inflammatory and autoimmune diseases. Here we describe an epigenetic mechanism that determines cell-type specific differences in IFN and IFN-stimulated gene expression in response to exogenous signals. more...