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Items: 4

1.

Resistance to thyroid hormone (RTH) and PPARa activation

(Submitter supplied) In this study we used the d337T TRb transgenic mouse that has been created to reproduce the human genetic disease known as resistance to thyroid hormone (RTH) as a model to determine if the d337T TRb mutation would have an effect on PPARa activation. A single amino acid deletion (d337T) abrogates thyroid hormone (T3) binding and transforms the thyroid hormone receptor (TRb) into a constitutive repressor. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2371
Platform:
GPL1261
28 Samples
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Series
Accession:
GSE3067
ID:
200003067
2.
Full record GDS2371

Dominant negative thyroid hormone receptor expression and PPARalpha activation effect on the heart

Analysis of hearts of dominant negative thyroid hormone receptor (TR) transgenics after treatment with the peroxisome proliferators activated receptor alpha (PPARalpha) agonist WY14643. Results provide insight into the crosstalk between TR and PPARalpha in the heart.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 strain sets
Platform:
GPL1261
Series:
GSE3067
28 Samples
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DataSet
Accession:
GDS2371
ID:
2371
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
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Platform
Accession:
GPL1261
ID:
100001261
4.

Control replicate 3

Organism:
Mus musculus
Source name:
Mouse heart
Platform:
GPL1261
Series:
GSE3067
Dataset:
GDS2371
Download data
Sample
Accession:
GSM67364
ID:
300067364
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