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Items: 3

1.

Decreasing Mutant ATXN1 Nuclear Localization Improves a Spectrum of SCA1-Like Phenotypes and Brain Region Transcriptomic Profiles

(Submitter supplied) Spinocerebellar ataxia type 1 (SCA1) is a dominant trinucleotide repeat neurodegenerative disease characterized by motor dysfunction, cognitive impairment, and premature death. Degeneration of cerebellar Purkinje cells is a frequent and prominent pathological feature of SCA1. We previously showed that transport of ATXN1 to Purkinje cell nuclei is required for pathology, where mutant ATXN1 alters transcription. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
120 Samples
Download data: TXT
Series
Accession:
GSE218303
ID:
200218303

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
11810 Series
657288 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

Hippocampus WT 10wk replicate 2

Organism:
Mus musculus
Source name:
hippocampus
Platform:
GPL24247
Series:
GSE218303
Download data
Sample
Accession:
GSM6738875
ID:
306738875

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db=gds|term=GSM6738875[Accession]|query=27|qty=2|blobid=MCID_664a1ac23844a3792a52088f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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