GSM680180[Accession] - GEO DataSets

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Items: 3

Select item 2000275441.

Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape

(Submitter supplied) We compared the expression of genes related to inflammatory cytotoxic functions between MSI and MSS (HLA class I negative and positive) gastrointestinal adenocarcinomas (GIACs), seeking evidence of differences in inflammatory mediators and cytotoxic T-cell responses. Twenty-two GIACs were divided into three study groups as a function of HLA class I expression and MSI phenotype. Comparison between eight high-level MSI (MSI-H) and 8 MSS/HLA+ (control) cancers identified 2170 differentially expressed genes (p< 0.05) after microarray analysis on the Affymetrix HG-U133-Plus-PM plate. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13158
22 Samples

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Accession:: GSE27544

ID:: 200027544

Analyze with GEO2R

Select item 1000131582.

[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html Annotations derived from HT_HG-U133_Plus_PM.na31.annot.csv Protocol: see manufacturer's web site