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Items: 4

1.

Comparison of HNF4 null mouse embryonic livers with control mouse embryonic livers

(Submitter supplied) To study the role of hepatic nuclear factor alpha (HNF4a in hepatogenesis, we used loxP-Cre technology to eliminate it from developing mouse livers. A comparison of control and experimental livers revealed that hepatocytes lacking HNF4a_failed to fully differentiate. Specifically, HNF4a null liver cells failed to express genes that are markers of mature hepatocytes including Gys2, Pck1, and G6pc. These cells also failed to form normal cellular junctions, which are critical for establishment of the hepatic epithelium [Parviz et al. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1916
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE3126
ID:
200003126
2.
Full record GDS1916

Hepatocyte nuclear factor 4 alpha knockout effect on the embryonic liver

Analysis of embryonic day 18.5 livers lacking hepatocyte nuclear factor 4 alpha (HNF4alpha). Cre/lox system used to knock out Hnf4a in liver. HNF4alpha is a nuclear hormone transcription factor. Results provide insight into the role of HNF4alpha in hepatogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE3126
6 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

HNF4 Control_1192

Organism:
Mus musculus
Source name:
E18.5 Embryonic Liver
Platform:
GPL1261
Series:
GSE3126
Dataset:
GDS1916
Download data: CEL
Sample
Accession:
GSM69793
ID:
300069793
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