GSM71500[Accession] - GEO DataSets

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Items: 4

Select item 2000031881.

Hypoxic regulation of gene expression is dominated by the HIF system and can be mimicked by DMOG

(Submitter supplied) The response of cells to hypoxia is characterised by co-ordinated regulation of many genes. Studies of the regulation of the expression of many of these genes by oxygen has implicated a role for the heterodimeric transcription factor hypoxia inducible factor (HIF). The mechanism of oxygen sensing which controls this heterodimeric factor is via oxygen dependent prolyl and asparaginyl hydroxylation by specific 2-oxoglutarate dependent dioxygenases (PHD1, PHD2, PHD3 and FIH-1). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2758 GDS2759 GDS2760 GDS2761
Platforms:: GPL2507 GPL96 GPL570
39 Samples

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Series

Accession:: GSE3188

ID:: 200003188

Select item 27582.

Hypoxia and 2-oxoglutrate-dependent dioxygenase inhibition (HG-U133A)

Analysis of MCF-7 breast cancer cells exposed to hypoxia or treated with the non-specific 2-oxoglutarate (2-OG) dependent dioxygenase inhibitor dimethyloxalylglycine. Results provide insight into the role of 2-OG dioxygenases in the regulation of gene expression during hypoxia.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 protocol sets

Platform:: GPL96
Series:: GSE3188
9 Samples

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DataSet

Accession:: GDS2758

ID:: 2758

Select item 1000000963.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...