GSM71540[Accession] - GEO DataSets

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Items: 4

Select item 2000031881.

Hypoxic regulation of gene expression is dominated by the HIF system and can be mimicked by DMOG

(Submitter supplied) The response of cells to hypoxia is characterised by co-ordinated regulation of many genes. Studies of the regulation of the expression of many of these genes by oxygen has implicated a role for the heterodimeric transcription factor hypoxia inducible factor (HIF). The mechanism of oxygen sensing which controls this heterodimeric factor is via oxygen dependent prolyl and asparaginyl hydroxylation by specific 2-oxoglutarate dependent dioxygenases (PHD1, PHD2, PHD3 and FIH-1). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2758 GDS2759 GDS2760 GDS2761
Platforms:: GPL2507 GPL570 GPL96
39 Samples

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Series

Accession:: GSE3188

ID:: 200003188

Select item 27602.

Hypoxia-inducible factor depletion (HG-U133 2.0)

Analysis of hypoxic MCF-7 breast cancer cells depleted for hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, or both HIF alpha subunits. Results provide insight into the extent of the role of HIF-1alpha and HIF-2alpha in the regulation of gene expression during hypoxia.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 protocol sets

Platform:: GPL570
Series:: GSE3188
12 Samples

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DataSet

Accession:: GDS2760

ID:: 2760

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...