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Items: 4

1.

Hypoxic regulation of gene expression is dominated by the HIF system and can be mimicked by DMOG

(Submitter supplied) The response of cells to hypoxia is characterised by co-ordinated regulation of many genes. Studies of the regulation of the expression of many of these genes by oxygen has implicated a role for the heterodimeric transcription factor hypoxia inducible factor (HIF). The mechanism of oxygen sensing which controls this heterodimeric factor is via oxygen dependent prolyl and asparaginyl hydroxylation by specific 2-oxoglutarate dependent dioxygenases (PHD1, PHD2, PHD3 and FIH-1). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS2758 GDS2759 GDS2760 GDS2761
Platforms:
GPL2507 GPL570 GPL96
39 Samples
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Series
Accession:
GSE3188
ID:
200003188
2.
Full record GDS2759

Hypoxia and 2-oxoglutrate-dependent dioxygenase inhibition (Human-6 BeadChip)

Analysis of MCF-7 breast cancer cells exposed to hypoxia or treated with the non-specific 2-oxoglutarate (2-OG) dependent dioxygenase inhibitor dimethyloxalylglycine. Results provide insight into the role of 2-OG dioxygenases in the regulation of gene expression during hypoxia.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 protocol sets
Platform:
GPL2507
Series:
GSE3188
6 Samples
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DataSet
Accession:
GDS2759
ID:
2759
3.

Sentrix Human-6 Expression BeadChip

(Submitter supplied) The Sentrix Human-6 BeadChip can be used to study expression of over 47,000 human transcripts. Researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by sequential hybridizations process called array decoding. Probes are fully screened all-full-length 50-mers. more...
Organism:
Homo sapiens
7 DataSets
55 Series
1420 Samples
Download data: CSV
Platform
Accession:
GPL2507
ID:
100002507
4.

MCF7_Normoxia_2_Illumina

Organism:
Homo sapiens
Source name:
MCF7, Normoxia 21% Oxygen
Platform:
GPL2507
Series:
GSE3188
Dataset:
GDS2759
Download data
Sample
Accession:
GSM71605
ID:
300071605
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db=gds|term=GSM71605[Accession]|query=1|qty=2|blobid=MCID_61ef4f47fc3dfd733a01c3d9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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