GSM71609[Accession] - GEO DataSets

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Items: 4

Select item 2000031881.

Hypoxic regulation of gene expression is dominated by the HIF system and can be mimicked by DMOG

(Submitter supplied) The response of cells to hypoxia is characterised by co-ordinated regulation of many genes. Studies of the regulation of the expression of many of these genes by oxygen has implicated a role for the heterodimeric transcription factor hypoxia inducible factor (HIF). The mechanism of oxygen sensing which controls this heterodimeric factor is via oxygen dependent prolyl and asparaginyl hydroxylation by specific 2-oxoglutarate dependent dioxygenases (PHD1, PHD2, PHD3 and FIH-1). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2758 GDS2759 GDS2760 GDS2761
Platforms:: GPL2507 GPL96 GPL570
39 Samples

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Series

Accession:: GSE3188

ID:: 200003188

Select item 27592.

Hypoxia and 2-oxoglutrate-dependent dioxygenase inhibition (Human-6 BeadChip)

Analysis of MCF-7 breast cancer cells exposed to hypoxia or treated with the non-specific 2-oxoglutarate (2-OG) dependent dioxygenase inhibitor dimethyloxalylglycine. Results provide insight into the role of 2-OG dioxygenases in the regulation of gene expression during hypoxia.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 protocol sets

Platform:: GPL2507
Series:: GSE3188
6 Samples

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DataSet

Accession:: GDS2759

ID:: 2759

Select item 1000025073.

Sentrix Human-6 Expression BeadChip

(Submitter supplied) The Sentrix Human-6 BeadChip can be used to study expression of over 47,000 human transcripts. Researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by sequential hybridizations process called array decoding. Probes are fully screened all-full-length 50-mers. more...