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Items: 4

1.

Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system

(Submitter supplied) Acute cognitive impairment (i.e., delirium) is common in elderly emergency department patients and frequently results from infections that are unrelated to the central nervous system. Since activation of the peripheral innate immune system induces brain microglia to produce inflammatory cytokines that are responsible for behavioral deficits, we investigated if aging exacerbated neuroinflammation and sickness behavior after peripheral injection of lipopolysaccharide (LPS). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1311
Platform:
GPL1261
12 Samples
Download data: XLS
Series
Accession:
GSE3253
ID:
200003253
2.
Full record GDS1311

Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior

Analysis of aged brain after activation of the peripheral innate immune system by intraperitoneal injection of E. coli lipopolysaccharide (LPS). Results provide insight into molecular events underlying severe behavioral deficits (delirium) common in older adults with systemic infections.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 development stage sets
Platform:
GPL1261
Series:
GSE3253
12 Samples
Download data
DataSet
Accession:
GDS1311
ID:
1311
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
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Platform
Accession:
GPL1261
ID:
100001261
4.

Brain_Adult_Salineip_4hr_mouse3(YP3_#60)

Organism:
Mus musculus
Source name:
Mouse brain, Adult, 4hr post Saline ip injection
Platform:
GPL1261
Series:
GSE3253
Dataset:
GDS1311
Download data
Sample
Accession:
GSM73001
ID:
300073001
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