GSM841640[Accession] - GEO DataSets

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Items: 4

Select item 2000352911.

Expression profiles of 7-day cultured HSPCs in the presence or absence of valproic acid and/or lithium

(Submitter supplied) Two small molecules, valproic acid (VPA) and lithium (Li), were tested to inhibit differentiation of hematopoietic stem/progenitor (HSPC) cells in culture. HSPCs exposed to VPA and Li during differentiation-inducing culture preserved an immature cell phenotype, provided radioprotection to lethally irradiated recipients and enhanced in vivo repopulating potential. Furthermore, VPA and Li synergistically preserved expression of stem cell-related genes and repressed genes involved in differentiation. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
12 Samples

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Series

Accession:: GSE35291

ID:: 200035291

Select item 2000340882.

The combination of valproic acid and lithium prevents hematopoietic stem/progenitor cell differentiation.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL6885 GPL6887
36 Samples

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Series

Accession:: GSE34088

ID:: 200034088

Select item 1000068853.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...