GSM843843[Accession] - GEO DataSets

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Items: 3

Select item 2000209451.

Effects of DAC treatment

(Submitter supplied) Reversal of gene promoter DNA hypermethylation and associated abnormal gene silencing is an attractive approach to cancer therapy. The DNA methylation inhibitor, decitabine (5-aza-2'-deoxycitidine), is proving efficacious for hematological neoplasms especially at lower, less toxic, doses. Experimentally, high doses induce rapid DNA damage and cytotoxicity, but these may not explain the prolonged time to response seen in patients. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

4 related Platforms
55 Samples

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Series

Accession:: GSE20945

ID:: 200020945

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000135342.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website